Role of IVIG in preventing exchange transfusions in Rh hemolytic disease.
نویسندگان
چکیده
منابع مشابه
بررسی اثر درمانی ایمونوگلوبولین وریدی بر روی زردی همولیتیک ایزوایمیون در نوزادان ترم
Background: Previous studies have demonstrated the efficacy of intravenous immunoglobulin therapy (IVIG) in decreasing the severity of neonatal immune hemolytic jaundice, the need for exchange transfusion, duration of phototherapy and hospital stay. Materials and methods: A randomized clinical trial was conducted in Taleghani Hospital in Tehran, between April 2003 and May 2004. Eighty full ter...
متن کاملIntravenous immunoglobulin in neonates with rhesus hemolytic disease: a randomized controlled trial.
BACKGROUND Despite limited data, international guidelines recommend the use of intravenous immunoglobulin (IVIg) in neonates with rhesus hemolytic disease. OBJECTIVE We tested whether prophylactic use of IVIg reduces the need for exchange transfusions in neonates with rhesus hemolytic disease. DESIGN AND SETTING We performed a randomized, double-blind, placebo-controlled trial in neonates w...
متن کاملIntravenous immunoglobulin in ABO and Rh hemolytic diseases of newborn.
OBJECTIVE To evaluate whether the use of intravenous immunoglobulin in newborn infants with isoimmune hemolytic jaundice due to Rh and ABO incompatibility is an effective treatment in reducing the need for exchange transfusion. METHODS This study included all direct Coombs' test positive Rh and ABO isoimmunized babies, who admitted in the Neonatal Intensive Care Unit of Ghaem Hospital of Mash...
متن کاملEfficacy of two dose regimes of intravenous immunoglobulin in Rh hemolytic disease of newborn--a randomized controlled trial.
OBJECTIVE To compare the effect of two dose regimes of IVIg (0.5 g/kg vs. 1g/kg given soon after birth) on duration of phototherapy in Rh-isoimmunized neonates 32 week and above gestation. DESIGN Randomized controlled trial. SETTING Tertiary care hospital. SUBJECTS Rh positive blood group neonates of gestation 32 weeks and above born to Rh negative mothers having positive Direct Coombs te...
متن کاملHemolytic Disease of the Newborn
Hemolytic disease of the newborn (HDN), with high potential for increased fetal loss is less common now, due to the universal screening for iso-sensitization and also because of appropriate use of antenatal anti-RhD antibody prophylaxis. There are other non-RhD antibodies that can cause HDN. In US, we occasionally encounter a highly sensitized fetus with significant morbidity and mortality. In ...
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ورودعنوان ژورنال:
- Indian pediatrics
دوره 42 1 شماره
صفحات -
تاریخ انتشار 2005